Condition
Gout
Gout is a type of inflammatory arthritis that causes sudden, severe pain, swelling, redness, and tenderness in joints, most often in the big toe. It occurs when uric acid crystals build up in the joints, triggering a painful inflammatory response.
Overview
85%
Average seven-year survival rate for people with gout
5.5%
The increase in the number of gout cases from 1990 to 2017
77% & 57%
The share of women and men, respectively, with gout who also have hypertension
In plain language
Gout is a form of inflammatory arthritis caused by elevated uric acid levels in the blood. It produces sudden, severe attacks of joint pain, swelling, and redness, most commonly affecting the big toe. Proper management can prevent long-term joint damage and recurrent flares.
Gout is a type of inflammatory arthritis caused by the buildup of uric acid crystals in the joints. This condition can lead to sudden, severe attacks of pain, swelling, redness, and tenderness, often affecting the big toe.
Uric acid is a byproduct of the body's breakdown of purines, substances found in certain foods. When the body produces too much uric acid or the kidneys are unable to eliminate it efficiently, crystals can form in the joints.
While gout can affect people of all ages, it is more common in men, especially middle-aged and older men. By understanding the risk factors and triggers of gout, individuals can take steps to prevent attacks and manage the condition effectively.
Key Information
Review the most relevant symptoms, risk factors, and common care approaches in one place.
Risk Factors
Several factors can increase the risk of developing gout, including:
Diet: A diet high in purines, such as red meat and seafood, can increase uric acid levels.
Alcohol consumption: Excessive alcohol consumption can raise uric acid levels.
Obesity: Being overweight or obese can increase the risk of gout.
Certain medications: Some medications, such as diuretics, can increase uric acid levels.
Medical conditions: Conditions like kidney disease and metabolic syndrome can contribute to gout.
Symptoms
A gout attack typically involves sudden, severe pain, swelling, redness, and tenderness in the affected joint, often the big toe. Other symptoms may include:
Joint pain: Intense pain, especially at night.
Joint swelling: The affected joint may appear swollen and red.
Limited range of motion: Difficulty moving the affected joint.
Fever: In some cases, a fever may accompany a gout attack.
Coping Strategies
Treatments That May Help
Start with the options that have more supporting research and then review the details with your care team.
Treatment Option
Collagen Peptides
Collagen peptides are easily absorbed protein fragments derived from collagen, the most abundant protein in the body. They provide amino acids that support skin elasticity, joint comfort, and connective tissue health.
5 studies
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Treatment Option
Curcumin (Turmeric extract)
Curcumin, the active compound in turmeric, has strong anti-inflammatory and antioxidant properties. It supports joint comfort, brain health, and cardiovascular wellness in older adults.
3 studies
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Treatment Option
Coenzyme Q10 (CoQ10)
Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant that supports mitochondrial energy production. It’s especially important for heart and brain health in older adults.
3 studies
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Treatment Option
Collagen Type II
Type II collagen is the primary collagen found in cartilage, providing the structural framework that gives joints their shock-absorbing properties. Supplementation supports joint comfort and cartilage maintenance.
1 study
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