Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing
Current Reviews in Musculoskeletal Medicine, 2025
Published: 11/11/2025
Summary
Comprehensive narrative review summarizing human and preclinical data on BPC-157. High transparency and relevance to musculoskeletal recovery in older adults.
Details
This review compiles current scientific evidence for BPC-157 in muscle, tendon, and bone repair. Authors conclude the peptide shows promise for musculoskeletal recovery, though more human research is essential.
Research Quality Score
Assessment
The study provides a comprehensive overview of BPC-157's potential in musculoskeletal healing. While it effectively compiles existing evidence, its narrative review design limits its methodological rigor. The study is transparent and relevant, with appropriate conflict of interest disclosures, but lacks new statistical analyses and replication potential.
Category Breakdown
| Category | Score | Max Points | Weight |
|---|---|---|---|
| Study Design / Evidence Level | 2 | 3 | 20% |
| Bias & Methods | 2 | 3 | 25% |
| Statistical Integrity | 1 | 2 | 15% |
| Transparency | 2 | 2 | 10% |
| Conflict of Interest Disclosure | 2 | 2 | 10% |
| Replication / External Validation | 0.5 | 1 | 5% |
| Relevance | 1 | 1 | 5% |
| Journal Quality | 2 | 2 | 10% |
Additional Notes
The study highlights the promise of BPC-157 but underscores the necessity for more rigorous human trials to validate preclinical findings.