Frailty in older adults: A systematic review of risk factors and early intervention pathways
Published: 12/15/2025
Summary
This review analyzed 50 global studies and found that frailty arises from multiple interconnected factors, including age, chronic illness, and social isolation. It highlights that frailty is often reversible through early screening, multidisciplinary care, and lifestyle changes.
Details
A 2025 systematic review identifying physiological, psychological, and social risk factors for frailty in older adults, proposing early intervention models for prevention and reversal.
Research Quality Score
Assessment
The study is a well-conducted systematic review that provides valuable insights into frailty in older adults. It is generally methodologically sound, though more detail on bias control and statistical methods would strengthen its reliability.
Category Breakdown
| Category | Score | Max Points | Weight |
|---|---|---|---|
| Study Design / Evidence Level | 2.5 | 3 | 20% |
| Bias & Methods | 2 | 3 | 25% |
| Statistical Integrity | 1.5 | 2 | 15% |
| Transparency | 1.5 | 2 | 10% |
| Conflict of Interest Disclosure | 2 | 2 | 10% |
| Replication / External Validation | 0.5 | 1 | 5% |
| Relevance | 1 | 1 | 5% |
| Journal Quality | 1.5 | 2 | 10% |
Additional Notes
The study could benefit from a more detailed methodology section and explicit mention of how bias was assessed in the included studies. Future research should focus on validating the proposed intervention pathways.