Condition
Peripheral Artery Disease (PAD)
A Serious Blood Flow Related Issue
Overview
8.5M
More than 8.5 million people in the U.S. have peripheral artery disease, according to the CDC.
2x risk
People with PAD have more than twice the risk of heart attack or stroke.
1 in 20
About 1 in 20 Americans over the age of 50 has PAD.
In plain language
Peripheral artery disease (PAD) is a circulatory condition that affects the blood flow to the limbs, primarily the legs. It occurs when the arteries that supply blood to the legs become narrowed or blocked, typically due to a buildup of plaque within the artery walls. This plaque, composed of cholesterol, fat, and other substances, restricts blood flow, depriving the legs of essential oxygen and nutrients.
Peripheral artery disease (PAD) is a common circulatory problem in which narrowed arteries reduce blood flow to the limbs, particularly the legs. It is usually caused by atherosclerosis, a buildup of fatty deposits in the artery walls.
PAD can lead to leg pain when walking (claudication), numbness, weakness, and, in severe cases, tissue damage. It’s a warning sign of widespread arterial disease and may signal increased risk for heart attack or stroke.
Early diagnosis and lifestyle changes can help manage PAD and reduce the risk of complications.
Key Information
Review the most relevant symptoms, risk factors, and common care approaches in one place.
Risk Factors
Several factors can increase the risk of developing PAD, including:
Smoking: Smoking is the strongest risk factor for PAD.
Age: The risk of PAD increases significantly with age.
Diabetes: People with diabetes are at significantly increased risk.
High blood pressure: High blood pressure can damage blood vessels.
High cholesterol: High cholesterol levels contribute to plaque buildup in the arteries.
Obesity: Obesity is associated with an increased risk of PAD.
Family history: A family history of PAD or other cardiovascular diseases increases the risk.
Symptoms
Common symptoms of peripheral artery disease include:
Intermittent claudication: Leg pain or cramping that occurs during exercise and subsides with rest. This is the most common symptom of PAD.
Numbness or tingling: Numbness or tingling in the legs or feet.
Coldness in the legs and feet: Decreased blood flow can make the legs and feet feel cold.
Weak pulse in the legs and feet: A weak or absent pulse in the feet may be a sign of PAD.
Non-healing sores on the legs and feet: Poor circulation can slow wound healing.
Erectile dysfunction: In men, PAD can affect blood flow to the penis, causing erectile dysfunction.
Treatments That May Help
Start with the options that have more supporting research and then review the details with your care team.
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